Blue rubber bleb nevus syndrome: Promising response to sirolimus

Background

Blue rubber bleb nevus syndrome is a rare disease involving venous malformations.

Case characteristics

We present a 6-year-old female with the syndrome, and consumptive coagulopathy.

Intervention/Outcome

After management with sirolimus, symptoms resolved.

Message

Sirolimus may be a valuable option for reducing bleeding complications and cosmetic sequelae for the patients with this syndrome.