Cholecystokinin-induced satiety in weanling rats |
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Authors: | Ilene L. Bernstein Elizabeth C. Lotter Janet C. Zimmerman |
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Affiliation: | 1. Department of Psychology, University of Washington USA;2. Department of Psychology, Northeastern University USA |
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Abstract: | Intraperitoneal injections fo the synthetic C-terminal octapeptide of cholecystokinin (CCK) into fasted 21-day-old weanling rats produced a significant suppression of intake of solid and liquid diets. Similar injections had no effect on water consumption of thirsty weanlings. The early appearance of CCK-induced satiety is consistent with the idea that this mechanism is responsible for the effectiveness of gastrointestinal factors in determining intake of very young rats. |
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Keywords: | Feeding behavior Satiety Cholecystokinin Weanling rats |
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