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Cholecystokinin-induced satiety in weanling rats
Authors:Ilene L. Bernstein  Elizabeth C. Lotter  Janet C. Zimmerman
Affiliation:1. Department of Psychology, University of Washington USA;2. Department of Psychology, Northeastern University USA
Abstract:Intraperitoneal injections fo the synthetic C-terminal octapeptide of cholecystokinin (CCK) into fasted 21-day-old weanling rats produced a significant suppression of intake of solid and liquid diets. Similar injections had no effect on water consumption of thirsty weanlings. The early appearance of CCK-induced satiety is consistent with the idea that this mechanism is responsible for the effectiveness of gastrointestinal factors in determining intake of very young rats.
Keywords:Feeding behavior  Satiety  Cholecystokinin  Weanling rats
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