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抑郁对老年高血压患者心率变异性及生活质量的影响
引用本文:周乐,王斌.抑郁对老年高血压患者心率变异性及生活质量的影响[J].心血管康复医学杂志,2013(5):475-477.
作者姓名:周乐  王斌
作者单位:上海市闸北区市北医院心内科,上海市200443
摘    要:目的:观察抑郁对老年高血压患者心率变异性及生活质量的影响。方法:150例老年高血压患者依据汉密尔顿抑郁量表测定结果进行分组,高血压合并抑郁者为高血压抑郁组(40例),高血压不合并抑郁者为单纯高血压组(110例),比较两组心率变异性及36项简易健康调查表(SF-36)评分的变化。结果:与单纯高血压组比较,高血压抑郁组在心率变异性方面:24h正常RR间期标准差ESDNN,(118.90±32.63)ms比(93.95±25.98)ms]、24h每5min正常RR间期平均值的标准差SDANN,(107.60±28.50)ms比(83.29±25.18)ms]、总频域值TP,(2283.62±965.31)ms^2比(1492.91±1004.69)ms^2]、极低频功率VLF,(1845.62±747.26)ms^2比(1132.41±680.34)ms^2]、低频功率ELF,(383.38±253.82)ms^2比(232.82±160.54)ms^2]明显降低(P〈0.05或P〈0.01);在生活质量的生理机能、生理职能、躯体疼痛、总体健康、活力、社会功能、情感职能和心理健康8个维度评分亦显著降低(P〈0.05或d0.01)。结论:抑郁降低了老年高血压患者的心率变异性,严重影响老年高血压患者的生活质量,应加强患者的心理疏导和社会支持。

关 键 词:高血压  抑郁  生活质量

Influence of depression on heart rate variability and quality of life in aged patients with hypertension
ZHOU Le,WANG Bin.Influence of depression on heart rate variability and quality of life in aged patients with hypertension[J].Chinese Journal of Cardiovascular Rehabilitation Medicine,2013(5):475-477.
Authors:ZHOU Le  WANG Bin
Institution:(Department of Cardiology, Shibei Hospital of Zhabei District, Shanghai, 200443, China)
Abstract:Objective: To study the influence of depression on heart rate variability (HRV) and quality of life in aged patients with hypertension. Methods: According to survey results of Hamilton depressive scale, a total of 150 aged patients with hypertension were divided into hypertension complicated depression group (n = 40) and pure hyperten-sion group (n=110). HRV and changes of 36-Item Short Form Health Survey (SF-36) scores were compared be-ween two groups. Results: Compared with pure hypertension group, there were significant decrease in SDNN (118.90 ± 32.63) ms vs. (93.95 ± 25.98) ms], SDANN (107.60 ± 28. 50) ms vs. (83.29 ± 25.18) ms], TP total power, (2283.62±965.31) ms2 vs. (1492.91± 1004.69) ms^2], VLF E (1845.62±747.26) ms^2 vs. (1132.41± 680.34) ms^2 andLF (383.38±253.82) ms^2 vs. (232.82± 160. 54) ms^2 in HRV, P〈0.05 or P〈0.01; and there significant decrease in eight dimension scores of quality of life (SF-36), including physical functioning, role-physical , bodily pain, general health, vitality, social functioning, role-emotional and mental health, P〈0.05 or 0.01, in hypertension complicated depression group. Conclusion: Depression decreases heart rate variability and se- riously affects their quality of life in aged patients with hypertension. Psychological regulation and social support should be enhanced in these patients.
Keywords:Hypertension  Depression  Quality of life
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