多囊卵巢综合征患者白细胞计数的变化特点

目的 探讨多囊卵巢综合征(PCOS)患者外周血白细胞(WBC)计数与体质量指数(BMI)、总睾酮(T)、雌二醇(E2)和促黄体生成素(LH)的关系。方法 对1016例PCOS患者(PCOS组)和1016例正常女性(对照组)的人体测量研究结果和基础内分泌指标进行回顾性分析，比较两组外周血WBC总数及其分类中性粒细胞(N)和淋巴细胞(L)计数，并分析PCOS患者外周血WBC总数及其分类N、L计数与BMI、T、E2、LH的相关性。结果 PCOS患者的外周血WBC总数和L计数明显高于正常女性(P<0.05)，WBC总数和L计数的升高与PCOS患者的BMI增加有关，与高水平E2和高水平LH不相关(P＞0.05)，WBC总数的升高与T呈正相关性(r=0.073,P<0.05)，L计数的升高与T不相关(P＞0.05)。结论 PCOS患者的WBC总数和淋巴细胞计数明显高于正常女性。

Changing Characteristics of peripheral white blood cell counts in patients with polycystic ovary syndrome

Objective To assess the relationships between body mass index(BMI),total testosterone(T),estradiol(E2),luteinizing hormone(LH) and peripheral white blood cell(WBC) count in patients with polycystic ovary syndrome(PCOS).Methods 1 016 women with PCOS and 1 016 age-matched healthy women participated in this study.Total WBC,neutrophil(N) and lymphocyte(L) count in the two groups were compared,and the correlation of BMI,T,E2,LH and total WBC,N,L count were analyzed in the PCOS group.Results Total WBC and L count increased significantly in the PCOS group compared to the control group(P<0.05).The increases of total WBC and L were correlated to BMI,but not correlated to E2(P>0.05) or LH(P>0.05).However,the increase of total WBC was positive correlated to T(r=0.073,P<0.05),and the increase of L was not correlated to T(P>0.05).Conclusion Total WBC and L count in the PCOS group increase significantly compared to the control group.