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防霉防蛀复合喷剂急性毒性实验研究
引用本文:马桢红,马良才.防霉防蛀复合喷剂急性毒性实验研究[J].医学动物防制,1999,15(10):527-529.
作者姓名:马桢红  马良才
作者单位:苏州市卫生防疫站 215003 (马桢红,马良才,潘恺友,黄永定),苏州市卫生防疫站 215003(陈淑玉)
摘    要:目的:测定百力牌防霉防蛀复合喷剂的急性毒性,对其安全性作出评价。方法:一次性灌胃给药、静式染毒柜染毒和直接涂(滴)药液。结果:小鼠急性经口毒性LD_(50)=4641.6mg/kg,95%可信限3480.2~6191.4mg/kg。急性吸入LC_(50)>10000mg/m~3。家兔皮肤刺激积分值为零,48h后的眼刺激平均指数为零。结论:本品属低毒级产品,对皮肤和眼无刺激作用,使用安全。

关 键 词:防霉防蛀剂  急性毒性  半数致死量  半数致死浓度

Studies on the Acute Toxicity of A Compound Spray of Preventing Mold and Moth Used in Sanitation
Ma Zhenhoung Ma Liangcai Pan Kaiyou et al.Studies on the Acute Toxicity of A Compound Spray of Preventing Mold and Moth Used in Sanitation[J].Chinese Journal of Pest Control,1999,15(10):527-529.
Authors:Ma Zhenhoung Ma Liangcai Pan Kaiyou
Institution:Suzhou Municipal Hygienic and Anti-epidemic Center 215003
Abstract:to determine the acute toxicity of the preventing mold and moth spray and evaluate its safety. Method:Single oral incubation,inhalation at stable concentration,smearing directly the rabbits' skin with the spray and putting drops in the conjunctiva crypt of rabbits. Result: Acute oral LD50 = 4641. 6mg/kg in mice, and the conference limit of 95% is 3480. 2-6191. 4mg/kg. Acute inhalation LC50 of mice is beyond 10000mg/m3. There is no irritation to the rabbits' skin or eyes. Conclusion-This product belongs to a lower toxicity substance through oral or inhalation, and it has not irritating to the rabbits' skin or eyes. It's safe used in sanitation.
Keywords:Preventing mold and moth spray Acute toxicity Median lethal dose Median Lethal concentration
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