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Treatment of obstructive sleep apnea syndrome with a Kampo-formula, San'o-shashin-to: A case report |
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| Authors: | Akito Hisanaga MD Osamu Saitoh MD PhD Hidemichi Fukuda MD PhD Kenzo Kurokawa MD Akihito Okabe MD Hiroyuki Tachibana MD Hirofumi Hagino P hD Tatsuo Mita MD Ikiko Yamashita CP Manabu Tsutsumi MD PhD Masayoshi Kurachi MD PhD & Takashi Itoh MD PhD |
| Institution: | Department of Neuropsychiatry, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan. |
| Abstract: | The following describes a 76-year-old male with obstructive sleep apnea syndrome successfully treated with a Kampo-formula, San'o-shashin-to (Formula medicamentorum tres ad dispellendi cordis). Polysomnography, performed before and after administration of San'o-shashin-to, revealed that the apnea index decreased from 11.1 events/hour to 4.1 events/hour, and that the apnea plus hypopnea index decreased from 18.4 events/hour to 10.7 events/hour. The patient was normo-weight (body mass index: 20.4 kg/m2), and events of sleep apnea and hypopnea were mostly noted during a non-rapid eye movement sleep. It is possible that San'o-shashin-to has some alleviating effects on the upper airway resistance during sleep. |
| Keywords: | Kampo obstructive sleep apnea syndrome polysomnography San'o-shashin-to |