Increment in Dialysate Sodium with Sodium Chloride or Bicarbonate Addition |
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Authors: | Rasib M. Raja Michael Fernandes Mark S. Kramer Jerry L. Rosenbaum Kevin Barber |
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Affiliation: | Division of Nephrology, Albert Einstein Medical Center, Philadelphia, Pennsylvania, U.S.A. |
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Abstract: | Abstract: Hemodialysis was performed in 12 patients for 2 weeks each utilizing acetate dialysate containing 134 mEq/L sodium and dialysate containing 143 mEq/L sodium, achieved by the addition of sodium chloride or sodium bicarbonate to the acetate dialysate. Intradialytic morbidity was lower, dialysis hypoxemia less marked, and predialysis blood pH higher with the bicarbonate-than with the chloride-added dialysate. The long-term use of sodium bicarbonate-added dialysate in three patients was safe. Dialysate pH adjustment was not required. These findings suggest that the addition of sodium bicarbonate (50–75 g) to acetate dialysate may be preferred to sodium chloride for increasing dialysate sodium in selected patients. |
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Keywords: | Hemodialysis High sodium dialysate Sodium bicarbonate Dialysis morbidity |
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