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用亚甲蓝判定乳腺癌前哨淋巴结转移的临床应用
引用本文:蒋新宇 林其声 黎犇犇. 用亚甲蓝判定乳腺癌前哨淋巴结转移的临床应用[J]. 中国医药指南, 2014, 0(20): 65-67
作者姓名:蒋新宇 林其声 黎犇犇
作者单位:福建省三明市第二医院普外科(福建中医药大学附属第五临床医学院),福建三明366000
摘    要:目的以亚甲蓝为示踪剂探测乳腺癌前哨淋巴结(sentinel lymph node,SLN),评价前哨淋巴结预测腋窝淋巴结转移的准确性。方法研究对象为自2011年6月份起我院普外科收治的100例cTis3N03N02M0的乳腺癌患者。使用亚甲蓝为示踪剂,进行前哨淋巴结活检,之后行腋窝清扫。结果 91例患者中成功地发现了SLN,SLN的数量为201个,平均每例2.20个。SLNB的灵敏度91.00%(91/100),准确率96.70%(88/91),假阴性率5.66%(3/53),阳性预测值为100%。结论使用亚甲蓝作为示踪剂能准确找到前哨淋巴结,并能较好的预测腋窝淋巴结转移情况。

关 键 词:前哨淋巴结  乳腺癌  亚甲蓝

Determined with Methylene Blue Sentinel Lymph Node Metastasis of Breast Cancer Clinical Applications
Affiliation:JIANG Xin-yu, LIN Qi-sheng, LI Ben-ben (The Second Hospital of Sanming(The Fifth Affiliated Hospital of Fujian University of Traditional Chinese Medicine), Sanming 366000, China)
Abstract:ObjectiveTo evaluate the performance and feasibility of sentinel lymph node (SLN) in breast cancer using methylene blue as a tracer.MethodsIn our Hospital, from June 2011 100 patients with cTis~3N0~2M0 underwent SLNB, which is followed by standard axillary dissection. Methylene blue was used to detect the SLN during surgery.ResultsThe sentinel node is successfully identiifed in 91% (91/100) of the patients. The number of sentinel nodes was 201, average 2.20, the sensitivity in the study was 91.00% (91/100), accuracy was 96.70% (88/91), false negative rate 5.66% (3/53), positive predictive value of 100%. ConclusionsThis method using methylene blue as a tracer can accurately ifnd the sentinel lymph node, and can predict axillary lymph node metastasis.
Keywords:Sentinel lymph node biopsy(SLNB)  Breast cancer  Methylene blue
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