| 白疕消软膏药材提取工艺的优化 |
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| 引用本文： | 张红,张耕,陈静萍. 白疕消软膏药材提取工艺的优化[J]. 医药导报, 2008, 27(4): 441-443. DOI: 10.3870/j.issn.1004-0781.2008.04.033 |
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| 作者姓名： | 张红 张耕 陈静萍 |
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| 作者单位： | 武汉市第一医院制剂中心,430022 |
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| 摘 要： | 目的 优化白疕消软膏药材提取工艺. 方法 以大黄素、大黄酚、苦参碱含量为指标,采用L9（34）正交实验法对其关键步骤如加水量、煎煮时间、煎煮次数、醇沉时加醇量等条件进行优选. 结果 优选工艺为加药材量8倍的水煎煮3次,每次1.5 h ,浓缩液加等量乙醇使沉淀. 结论 该实验优化的提取工艺合理可行.
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| 关 键 词： | 白疕消软膏 大黄素 大黄酚 苦参碱 正交实验 提取工艺 |
| 文章编号： | 1004-0781(2008)04-0441-03 |
| 收稿时间： | 2007-08-20 |
| 修稿时间： | 2007-08-20 |
Optimization of Extraction Process for Baibixiao Qintment |
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| ZHANG Hong,ZHANG Geng,CHEN Jing-ping. Optimization of Extraction Process for Baibixiao Qintment[J]. Herald of Medicine, 2008, 27(4): 441-443. DOI: 10.3870/j.issn.1004-0781.2008.04.033 |
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| Authors: | ZHANG Hong ZHANG Geng CHEN Jing-ping |
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| Abstract: | Objective To optimize the extraction process of baibixiao qintment. Methods The optimum extraction process including water volume,decocting time and times and capacity of alcohol was determined by using the L9(34) orthogonal test and regarding contents of emodin,chrysophanol and matrine as parameters. Results The optimum process was that decocting for 3 times,1.5 h by each with water 8 times volume of herbal weight,and precipitating with the equivalent alcohol. Conclusion The optimized extracting conditions is reasonable and practicable. |
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| Keywords: | Baibixiao qintment Emodin Chrysophanol Matrine Orthogonal test Extracting process |
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