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Neisseria meningitidis ST-11 Clonal Complex,Chile 2012 |
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| Authors: | Pamela Araya Jorge Fernández Felipe Del Canto Mabel Seoane Ana B. Ibarz-Pavón Gisselle Barra Paola Pidal Janepsy Díaz Juan C. Hormazábal María T. Valenzuela |
| Affiliation: | Instituto de Salud Pública de Chile, Santiago, Chile (P. Araya, J. Fernández, M. Seoane, G. Barra, P. Pidal, J. Díaz, J.C. Hormazábal, M.T. Valenzuela); ;Universidad de Chile, Santiago (F. Del Canto); ;Pan American Health Organization, Washington, DC, USA (A.B. Ibarz-Pavón) |
| Abstract: | Serogroup W Neisseria meningitidis was the main cause of invasive meningococcal disease in Chile during 2012. The case-fatality rate for this disease was higher than in previous years. Genotyping of meningococci isolated from case-patients identified the hypervirulent lineage W:P1.5,2:ST-11, which contained allele 22 of the fHbp gene. |
| Keywords: | Neisseria meningitidis bacteria serogroup W invasive meningococcal disease ST-11 sequence type hyperinvasive lineage clonal complex Chile |