Perineal soft tissue infections |
| |
| Affiliation: | 1. Department of Colon and Rectal Surgery, The Cleveland Clinic Foundation, 9500 Euclid Ave Desk A-30, Cleveland, OH 44195, USA;2. The Cleveland Clinic Foundation, 9500 Euclid Avenue Desk A-30, Cleveland, OH 44195, USA;1. Columbia-Cornell NYP Colorectal Fellowship Program, Division of Colorectal Surgery, Columbia University Medical Center/New York Presbyterian Hospital, New York City, NY, USA;2. Division of Colorectal Surgery, Columbia University Medical Center/Mailman School of Public Health, New York City, NY, USA;3. Center for Innovation and Outcomes Research, Columbia University Medical Center/New York Presbyterian Hospital, New York City, NY, USA;1. Surgical Outcomes Research Centre (SOuRCe), Sydney, Australia;2. The Institute of Academic Surgery at RPA, Sydney, Australia;3. Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, Australia;4. University of Sydney, Sydney, Australia;1. American College of Surgeons, Division of Research and Optimal Patient Care, Chicago, IL USA;2. University of Chicago Medical Center, Department of Surgery, Chicago, IL USA;3. University of Alabama at Birmingham Medical Center, Department of Surgery, Birmingham, AL USA;4. David Geffen School of Medicine, University of California Los Angeles, Department of Surgery, and VA Greater Los Angeles Healthcare System, Los Angeles, California USA |
| |
| Abstract: | Fournier's gangrene (FG) is an aggressive necrotizing soft tissue infection of the perineum. FG takes hold as a mixture of pathogenic organisms enter the host via injured gastrointestinal or genitourinary mucosa. After soft tissue insult, a synergistic, polymicrobial infection destroys tissue through an obliterative endarteritis. FG particularly affects older, obese men with type 2 diabetes mellitus, but can affect everyone. Special populations at risk include patients who have undergone gender reassignment surgery. Early, aggressive debridement and fluid resuscitation are mandatory. Careful decisions must be made regarding the fecal stream, antibiosis, topical coverings and the use of adjunctive therapy. While untreated FG is certainly fatal, with effective diagnosis and treatment survival rates approach 95%. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
