| 糖组和糖组学 |
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| 引用本文： | 王克夷,杜昱光. 糖组和糖组学[J]. 医学分子生物学杂志, 2004, 1(5): 261-264 |
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| 作者姓名： | 王克夷 杜昱光 |
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| 作者单位： | 中国科学院上海生命科学院生物化学与细胞生物学研究所,上海市,200031;中国科学院大连化学物理研究所,辽宁省大连市,116011;中国科学院大连化学物理研究所,辽宁省大连市,116011 |
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| 摘 要： | 本文简单地介绍了糖组和糖组学的研究内容和差别及研究糖组和糖组学的战略和方法。质谱、亲和层析、毛细管电泳、芯片和微流技术已成为糖组和糖组学研究中的有用工具。在糖组学的研究中 ,糖基转移酶和糖结合蛋白是承上启下的两类蛋白质 ,因此 ,糖组学的研究与蛋白质组学、基因组学密不可分。
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| 关 键 词： | 糖组 糖组学 质谱 亲和层析 毛细管电泳 芯片和微流技术 |
| 修稿时间： | 2004-08-23 |
Glycome and Glycomics |
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| WANG Keyi ,,DU Yuguang Insitute of Biochemistry and Cell Biology,Shanghai Institutes of Biological Sciences,Chinese Academy of Science,Shanghai,,China Dalian Institute of Chemical Physics,Chinese Academy of Science,Dalian,,China. Glycome and Glycomics[J]. Journal of Medical Molecular Biology, 2004, 1(5): 261-264 |
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| Authors: | WANG Keyi DU Yuguang Insitute of Biochemistry Cell Biology Shanghai Institutes of Biological Sciences Chinese Academy of Science Shanghai China Dalian Institute of Chemical Physics Chinese Academy of Science Dalian China |
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| Affiliation: | WANG Keyi 1,2,DU Yuguang 2 1Insitute of Biochemistry and Cell Biology,Shanghai Institutes of Biological Sciences,Chinese Academy of Science,Shanghai,200031,China 2Dalian Institute of Chemical Physics,Chinese Academy of Science,Dalian,116011,China |
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| Abstract: | The objects of glycome and glycomics, the differences between them, as well as the strategies and methods in this field, are discussed in this paper. Some technologies, such as mass spectroscopy,affinity chromatography, capillary electrophoresis, microarray and microfluid have become useful tools in glycome and glycomics. In glcomics, glycotransferases and carbohydrate-binding proteins are two important kinds of proteins, so glycomics is closely connected with proteomics and genomics. |
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| Keywords: | glycome glycomics mass spectroscopy affinity chromatography capillary electrophoresis microarray and microfluidics |
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