兔眼房水引流至不同部位的降眼压效果

目的 观察并比较3种途径（引流至角膜缘、赤道部及眼后节）植入医用硅胶管降眼压的效果。方法 选择健康新西兰白兔45只，单眼植入医用硅胶管将房水引流。根据植入途径分为角膜缘组、赤道部组和眼后节组，每组15只。结果 对各实验组术前、术后眼压值进行统计对比，术后4周内眼后节组降眼压幅度最大（26.6%），赤道部组次之（16.2%），角膜缘组最小（1.2%）；术后1、2和4周，赤道部组、角膜缘组、眼后节组的术前、术后眼压值比较差异均有统计学意义（P<0.01）；术后4周，眼后节组眼压下降幅度最大，且各组间眼压值差异均有统计学意义（P<0.01）。结论 将房水引流至眼后节时眼压下降幅度大，可为临床手术提供参考。

Effects of aqueous humor drainage to different parts of rabbit eye on intraocular pressure drop

Objective To observe and compare the effects of intraocular pressure (IOP) drop when the aqueous humor was drained to limbus, ambitus and posterior segment of rabbit eye by implanting medical silicone tube. Methods Forty-five healthy New Zealand white rabbits were chosen for the experimental group, each with the medical silicone tube implanted in one eye. According to different implanting ways, the rabbits were divided into the limbus group, ambitus group and posterior segment group respectively, with 15 rabbits in each group. Results According to statistical comparison of preoperative and postoperative IOP values among the 3 groups within 4 weeks, the IOP of the posterior segment group was decreased most by 26.6%, and that of the ambitus group and limbal group was decreased by 16.2% and 1.2%, respectively. The differences between the preoperative and postoperative IOP in first, second and fourth week were statistically significant (P<0.01) for all three groups. The IOP of the posterior segment group after 4 weeks was decreased most, and there were significant differences in IOP values among three groups (P<0.01). Conclusions The greatest IOP drop occurred when the aqueous humor was drained to the posterior segment of the rabbit eye, and this result could provide some reference for the clinical surgery.