应用Apollo球囊扩张支架治疗症状性颅内椎-基底动脉重度狭窄的临床研究

目的探讨应用Apollo球囊扩张支架治疗症状性颅内椎-基底动脉重度动脉粥样硬化性狭窄的疗效。方法选择我院脑血管病中心2011年11月～2012年5月收治的42例症状性颅内椎-基底动脉重度(狭窄≥70%)动脉粥样硬化性狭窄患者,应用Apollo球囊扩张支架行血管内支架成形术治疗。其中狭窄位于基底动脉17例,颅内椎动脉25例。结果本组41例成功置入支架,1例因支架无法到位而未能完成手术,支架置入成功率为97.6%(41/42)。术后30 d内的并发症发生率为4.9%(2/41),其中,卒中率为2.4%(1/41),短暂性脑缺血发作(TIA)为2.4%(1/41),无死亡病例。对41例手术成功患者临床随访2～8个月,效果良好,无新发卒中及TIA发作病例。结论应用Apollo球囊扩张支架治疗症状性颅内椎-基底动脉重度动脉粥样硬化性狭窄是安全有效的。

Clinical research of application of Apollo balloon expansion stents for treatment of symptomatic intracranial vertebrobasilar artery severe narrow

Objective To evaluate the efficacy of angioplasty with Apollo stent for the treatment of intracranial vertebrobasilar arterial stenosis. Methods A total of 42 patients with symptomatic intraeranial vertebrobasilar arterial stenosis received angioplasty and stenting with Apollo stent. The locations of stenoses were basilar artery in 17 and intracranial segment of vertebral artery in 25. All patients with severe atherosclerotic stenosis （stenosis ≥ 70%）. Results Successful Apollo stent placement was achieved in 41 cases （97.6%）, 1 case failed due to the inaccessibility of the Apollo stent to the fight place. Complications were found in 2 patients （4.9%） in the first 30 days; stroke was found in 1 patient （2.4%）; TIA was found in 1 patient （2.4%） and no death occurred. 41 cases succeeded in operation were followed up of 2-8 months and no new stroke or TIA was found. Conclusion Angioplasty and stenting with Apollo stent for treating intraeranial vertebrobasilar stenosis are safe and effective.