骨科内固定术后感染的危险因素分析及临床意义

目的探讨骨科内固定术后感染的危险因素,为临床防治骨科内固定术后感染提供借鉴。方法回顾性收集我院2004年1月～2010年12月行内固定术后发生感染患者52例,同期收集我科未感染手术患者104例,对发生感染病例的是否开放、是否污染、内固定材质等资料进行单因素分析,对有显著相关因素再进行多因素分析。结果单因素分析显示:是否开放、伤口污染、是否多处骨折、手术操作时间、使用激素、糖尿病、合并基础疾病与骨科内固定术后感染显著相关。多因素分析显示:伤口污染、手术操作时间、使用激素、糖尿病、合并基础疾病为内固定术后感染独立危险因素。结论骨科内固定术后感染治疗棘手,重视这些危险因素在骨科内固定术后感染的参考价值,将可能进一步减少内固定术后感染的发生概率。

Risk factors analysis and clinical significance of infection after orthopedic internal fixation

Objective To investigate the risk factors of the infection after orthopedic internal fixation, provide a reference for prevention of infection after orthopedic internal fixation. Methods 52 case of infection patients after internal fixation in our hospital from Januan 2004 to December 2010 were retrospectively collected, and at the same time, 104 cases of no-in- fected in our department were collected. Univariate analysis on open or not, polluted or not, internal fixed material and oth- er information were took. Multivariate analysis on significant related factors were took. Results Univariate analysis showed： open or not, wound polluted or not, multiple fractures or not, operation time, using of hormones, diabetes and merger basic disease were significantly associated with infections after orthopedic internal fixation. Multivariate analysis showed： wound polluted or not, multiple fractures or not, operation time, using of hormones, diabetes and merger basic disease were inde- pendent risk factor of the after orthopedic internal fixation. Conclusion Treatment of infection after orthopedic internal fix- ation is difficult. Paying attention to the reference value of these risk factors in infection after the internal fixation may fur- ther reduce the occurrence of infection after the internal fixation.