| 下呼吸道感染病原菌鉴定与耐药性分析 |
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| 引用本文： | 张晓丽,王勇,郭宇航,高荣升,周薇薇,王晓红,付成显. 下呼吸道感染病原菌鉴定与耐药性分析[J]. 中华医院感染学杂志, 2011, 21(1): 160-162 |
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| 作者姓名： | 张晓丽 王勇 郭宇航 高荣升 周薇薇 王晓红 付成显 |
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| 作者单位： | 佳木斯大学附属第一医院检验科,黑龙江,佳木斯,154003 |
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| 基金项目： | 黑龙江省卫生厅科研项目，佳木斯大学科学技术研究项目 |
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| 摘 要： | 目的了解医院下呼吸道感染病原菌的现状和体外耐药性,分析产超广谱β-内酰胺酶(ESBLs)的产生情况,为临床的合理用药提供参考。方法采用全自动微生物鉴定仪对从门诊和住院下呼吸道感染患者痰标本中分离的病原菌进行鉴定及药物敏感试验,并用双纸片扩散法对产ESBLs菌株进行确证。结果共检出684株病原菌,革兰阴性杆菌占主导地位(62.1%);产ESBLs大肠埃希菌检出率为53.6%,肺炎克雷伯的检出率为34.3%;革兰阳性球菌对万古霉素全部敏感,革兰阴性杆菌对亚胺培南的耐药率较低,对酶抑制剂类抗菌药物较敏感,对第一、二代头孢菌素耐药率较高。结论随着抗菌药物的持续使用,呼吸道感染的产ESBLs大肠埃希菌耐药情况日趋严重,耐药性监测对临床合理应用抗菌药物具有指导意义。
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| 关 键 词： | 下呼吸道感染 超广谱β-内酰胺酶 耐药性 |
Identification of pathogenic bacteria causing lower respiratory tract infection and drug resistance |
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| ZHANG Xiao-li,WANG Yong,GUO Yu-hang,GAO Rong-sheng,ZHOU Wei-wei,WANG Xiao-hong,FU Cheng-xian. Identification of pathogenic bacteria causing lower respiratory tract infection and drug resistance[J]. Chinese Journal of Nosocomiology, 2011, 21(1): 160-162 |
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| Authors: | ZHANG Xiao-li WANG Yong GUO Yu-hang GAO Rong-sheng ZHOU Wei-wei WANG Xiao-hong FU Cheng-xian |
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| Affiliation: | ZHANG Xiao-li,WANG Yong,GUO Yu-hang,GAO Rong-sheng,ZHOU Wei-wei,WANG Xiao-hong,FU Cheng-xian(The First Affiliated Hospital of Jiamusi University,Jiamusi,Heilongjiang 154003,China) |
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| Abstract: | OBJECTIVE To investigate the clinical characteristic and antimicrobial resistance of pathogenic bacteria causing lower respiratory tract infection,in order to provide reference for the clinical application of drugs.METHODS The strains of pathogenic bacteria were detected and their sensitivity to antibiotics was determined by Walkway 40 automatic bacterium identifying and drug sensitivity analyzing systems,then the specimens in which bacteria was detected and the result of sensitivity to antibiotics were ana... |
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| Keywords: | Lower respiratory tract infection ESBLs Drug resistance |
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