头颈部癌患者心理状况与生存质量关系

目的 探讨头颈部癌治疗后患者心理状况与生存质量之间的关系。方法 对中国人民解放军济南军区第四五六医院肿瘤科复诊的110例头颈部癌术后或放化疗后的患者及105名健康对照进行问卷调查。结果 头颈部癌患者生存质量总分为(717.45±109.63)分,对照组总分为(867±90.64)分,头颈部癌患者各个领域生存质量指标均低于对照组,差异有统计学意义(P<0.05);Spearman相关分析表明,焦虑及抑郁与患者生存质量大多数维度呈相关关系(P<0.05);Logistic回归分析表明,抑郁、焦虑是患者生存质量的主要影响因素,标准回归系数分别为-0.597、-0.830;头颈部癌患者心理状况与生存质量密切相关。结论 心理干预可作为生存质量的干预手段之一;改善患者的心理状况可以提高其生存质量水平。

Relationship between mental status and quality of life in patients with head-neck carcinoma

Objective To investigate the correlation between mental status and quality of life(QOL)in patients with head and neck carcinoma after treatment.Methods Questionnaires were administered to 116 patients after operation or radiotherapy and chemotherapy in the Department of Oncology,No.456 Hospital of Ji'nan Military Region of People's Liberation Army.Results The total scores of the University of Washington Quality of Life Questionnaire(UW-QOL)in the patients and the controls were 717.45±109.63 and 867±90.64,respectively.Compared with the control,the patients had lower scores in every domain of life quality(P<0.05).Significant correlations were found between anxiety,depression and the most domains of the questionnaire(P<0.05)based on the analyses of Spearman correlation.Anxiety and depression were main influencing factors to the quality of life in the patients according to the results of logistic regression analyses with the standardized regression coefficients of-0.597 and-0.830,respectively.There was a close relationship between mental status and the quality of life in the patients.Conclusion Mental health promotion could be an effective intervention method and better mental health can improve the QOL of the patients with head and neck carcinoma.