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咽炎咀嚼片质量标准的建立
引用本文:杨志福,曹军,杨静,曹金一,李华,陆杨,马善波,文爱东. 咽炎咀嚼片质量标准的建立[J]. 中国药师, 2012, 15(3): 327-329
作者姓名:杨志福  曹军  杨静  曹金一  李华  陆杨  马善波  文爱东
作者单位:第四军医大学西京医院药剂科 西安 710032
基金项目:陕西省科技攻关课题(编号:2009K13-01)
摘    要:目的:咽炎咀嚼片质量标准的建立.方法:采用TLC法对处方中的甘草、金银花两种组分进行定性鉴别:采用高效液相色谱法对处方中的绿原酸进行了含量测定.结果:薄层色谱斑点清晰,阴性对照无干扰,高效液相色谱法线性关系良好,平均回收率为99.61%,RSD为0.97%.结论:本法定性、定量检测准确、可靠,能有效控制咽炎咀嚼片的质量.

关 键 词:咽炎咀嚼片  质量标准  薄层色谱法  高效液相色谱法
收稿时间:2011-10-30
修稿时间:2011-12-19

Study on Quality Standard of Phyaryngitis Chewable Tablets
Yang Zhifu,Cao Jun,Yang Jing,Cao Jinyi,Li Hu,Lu Yang,Ma Shanbo and Wen Aidong. Study on Quality Standard of Phyaryngitis Chewable Tablets[J]. China Pharmacist, 2012, 15(3): 327-329
Authors:Yang Zhifu  Cao Jun  Yang Jing  Cao Jinyi  Li Hu  Lu Yang  Ma Shanbo  Wen Aidong
Affiliation:Department of Pharmacy, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China;Department of Pharmacy, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China;Department of Pharmacy, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China;Department of Pharmacy, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China;Department of Pharmacy, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China;Department of Pharmacy, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China;Department of Pharmacy, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China;Department of Pharmacy, Xijing Hospital, the Fourth Military Medical University, Xi'an 710032, China
Abstract:Objective:To establish the quality standard of phyaryngitis chewable tablets.Method:Flos Lonicerae and Radix Glycyrrhizae in phyaryngitis chewable tablets were identified by TLC,and the content of chlorogenic acid was determined by HPLC.Result: The TLC spots were clear with no interference by the negative control.The linear relationship of chlorogenic acid was promising. The average recovery was 99.61%with RSD of 0.97%.Conclusion:The method is exact and credible,and could effectively control the quality of pharyngitis chewable tablets.
Keywords:Pharyngitis chewable tablets   Quality standard   TLC   HPLC
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