淡色库蚊对残杀威的抗性选育及交互抗性研究

目的探讨淡色库蚊残杀威抗性品系对5种化学杀虫剂的抗性发展及交互抗性，为合理使用杀虫剂提供依据。方法采用WHO标准生物测试法，计算LC50方程及抗性倍数。结果经过43代的选育，抗残杀威品系的抗性达11．26倍。在21代时，对残杀威、DDVP、氯氰菊酯、三氯杀虫酯、溴氰菊酯的抗性倍数分别为9．54、2．68、7．00、1．74、1．70；到第30代时分别为11．34、2．85、8．07、2．00、1．80；到39代时对残杀威的抗性为11．78倍，对DDVP和氯氰菊酯的抗性分别为3．35和9．71倍。结论长期使用一种杀虫剂易产生抗性，亦对其他杀虫剂产生交互抗性，用药时应注意种类的选择。

Selection for Resistance to Propoxur in Culex pipiens pallens and It's Cross-Resistance

Objective To study the resistance development and cross-resistance of Propoxur-resistant Culex pipiens pallens to several chemical insecticides for their rational use. Methods WHO standard bioassay was employed to calculate LC_ 50 , regression equation and resistance index. Results The resistance index of Culex pipiens pallens rose up to 11.26 folds after 43 generation's propoxur selection. The indexes of the resistant mosquito to propoxur, DDVP, cypermethrin, acetofenate and deltamethrin were 9.54 , 2.68 , 7.00 , 1.74 , 1.70 folds in the 21 generation and 11.34 , 2.85 , 8.07 , 2.00 , 1.80 folds in the 30 generation, respectively. In the 39 generation, those were 11.78 folds to propoxur, 3.35 to DDVP and 9.71 to cypermethrin. Conclusion The resistance and cross-resistance were easily developed for a long term use of one kind of insecticide, which showed that the insecticides should be rationally used in mosquito control to delay the development of the resistance and cross-resistance.