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可舒对小鼠急性乙醇中毒的防治作用
引用本文:曾明,徐娟,王金萍,边佳明,费燕,赵小宇,许景蜂. 可舒对小鼠急性乙醇中毒的防治作用[J]. 中国药房, 2005, 16(9): 664-666
作者姓名:曾明  徐娟  王金萍  边佳明  费燕  赵小宇  许景蜂
作者单位:1. 北京军区总医院药理科,北京市,100700
2. 第二军医大学药学院,上海市,200433
摘    要:目的观察可舒对小鼠急性乙醇中毒的预防和治疗作用。方法建立急性乙醇中毒小鼠模型,将小鼠随机分为模型组和可舒高、中、低剂量组,比较各组的耐受时间、维持时间及血中乙醇浓度。结果与模型组比较,可舒组耐受时间延长、维持时间缩短,血中乙醇浓度降低。结论可舒对急性乙醇中毒具有显著的预防和治疗作用,且预防作用优于治疗作用。

关 键 词:可舒  乙醇中毒  预防  治疗
文章编号:1001-0408(2005)09-0664-03
修稿时间:2004-09-15

The Preventive and Therapeutic Effect of Keshu on Acute Alcoholism Mice
ZENG Ming,XU Juan,WANG Jinping,BIAN Jiaming,XU Jingfeng,FEI Yan,ZHAO Xiaoyu. The Preventive and Therapeutic Effect of Keshu on Acute Alcoholism Mice[J]. China Pharmacy, 2005, 16(9): 664-666
Authors:ZENG Ming  XU Juan  WANG Jinping  BIAN Jiaming  XU Jingfeng  FEI Yan  ZHAO Xiaoyu
Abstract:OBJECTIVE:To observe the preventive and therapeutic effect of Keshu on acute alcoholism mice.METHODS:Acute alcoholism mice model was established,and randomly divided mice into model group and high,middle,low dosage of Keshu group;the tolerance time,lasting time and the concentration of alcohol in blood were compared among each group.RE-SULTS:Compared with the model group,the tolerance time has been prolonged,the lasting time has been shortened and the blood concentration of alcohol has been lowered in Keshu group.CONCLUSION:Keshu has an obvious preventive and thera-peutic effect on acute alcoholism,the preventive effect of which outweighs the therapeutic effect.
Keywords:Keshu  Alcoholism  Preventive effect  Therapeutic effect
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