肺癌肉瘤二例报告并文献复习

目的 :探讨肺癌肉瘤的临床病理特点及其组织来源。方法 :对 2例肺癌肉瘤进行临床病理资料回顾性分析、光镜观察 ,并结合文献对其组织发生、临床表现、诊断及治疗方法进行分析。结果 :肺癌肉瘤主要症状为咳嗽、胸痛、血丝痰等 ,X线示病灶边缘清楚 ,有分叶。镜下见癌与肉瘤共存 ,2例均可见胚胎性支气管结构。结论 :肺癌肉瘤临床特征与肺癌不易区别且预后差 ,外科手术是其主要的治疗手段。组织学特征支持单克隆起源学说。

Pulmonary Carcinosarcoma 2 Case Report with Literature Review

Objective To investigate the clinicopathological features and histogenesis of pulmonary carcinosarcoma.Methods 2 cases with pulmonary carcinosarcoma were analysed retrospectively in their clinicopathological data and light microscopic examinations,and reviewing literature to analyse their histologic,clinical feature,diagnosis and treament.Results The main symptoms of pulmonary carcinosarcoma were cough,expetoration,sometimes bloody phlegm.which was easy to be confused with lung cancer.X ray showed the margin of the focuse were clear.Under microscope mainly consisted of adenocarcinoma and fibrosarcoma,the fetal bronchus like structure was seen in the 2 cases.Conclusion Pulmonary carcinosarcoma is easily confused with lung cancer in clinical characteristics.Prognosis is very poor surgical resection is the main method of diagnosis and treatment,and its histological features support the hypothesis of monoclonal origin.