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血府逐瘀胶囊干预高血压病左室舒张功能及心室重构的临床研究
引用本文:孙伯青. 血府逐瘀胶囊干预高血压病左室舒张功能及心室重构的临床研究[J]. 南京中医药大学学报, 2009, 25(1)
作者姓名:孙伯青
作者单位:江苏省昆山市中医医院,江苏,昆山,215300
基金项目:江苏省昆山市社会发展基金 
摘    要:目的 观察血府逐瘀胶囊联合氨氯地平(络活喜)、苯那普利(洛汀新)治疗对高血压病左室舒张功能及心室重构逆转的影响.方法 选取60例未经正规治疗的高血压病患者随机分为治疗观察组(A组)、治疗对照组(B组)各30例,A、B2组均服用氨氯地平、苯那普利,A组加服血府逐瘀胶囊.2组均在治疗前、治疗6个月、治疗10个月观察对血压、左室舒张功能、心室重构的影响.结果 A、B组在稳定降压的同时均能逆转左室肥厚(LVH)及改善舒张功能,而且随着用药时间的延长,LVH逆转及E/A比值升高越明显,A组治疗后IVST、LVDd、LVMI下降幅度及E/A比值上升幅度均大于B组(P<0.05),A组LVDd逐渐缩小,提示逆转LVH、改善心脏舒张功能方面较B组为优.结论 治疗高血压病联合使用血府逐瘀胶囊能更有效地逆转心室重构、改善心功能.

关 键 词:高血压  血府逐瘀胶囊  舒张功能  左室肥厚

A Clinical Study on Effect of Xuefu Zhuyu Capsule in Interfering with Left Ventricular Diastolic Function and Remodeling in Patients with Hypertension
SUN Bo-qing. A Clinical Study on Effect of Xuefu Zhuyu Capsule in Interfering with Left Ventricular Diastolic Function and Remodeling in Patients with Hypertension[J]. Journal of Nanjing University of Traditional Chinese Medicine(Natural Science), 2009, 25(1)
Authors:SUN Bo-qing
Affiliation:Kunshan Municipal TCM Hospital;Kunshan;Jiangsu;215300;China
Abstract:OBJECTIVE To observe the effect of Xuefu Zhuyu Capsule combined with Amlodipin(Norvasc) and Benazepril(Lotensin) on the diastolic function and remodeling of left ventricule in patients with hypertension.MRTHOD Sixty hypertension patients without previous routine treatment were randomly and evenly divided into a treatment observation group(Group A) and a treatment control group(Group B).Both groups were given amlodipin and benazepril,with the patients in Group A taking Xuefu Zhuyu Capsule additionally.The th...
Keywords:hypertension  Xuefu Zhuyu Capsule  diastolic function  left ventricular hypertrophy  
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