NTI-tss和稳定咬合板治疗磨牙症的多导睡眠监测研究

目的比较NTI-tss咬合板和稳定咬合板（OS）对于磨牙症的短期疗效。方法10例磨牙症患者采用随机自身交叉对照试验,戴用NTI-tss和OS治疗各1周,于戴用咬合板前一晚、戴用当晚和戴用1周后进行多导睡眠监测,计算磨牙指数和睡眠微觉醒指数,数据采用SAS 9.1混合效应模型进行分析。结果两种咬合板在戴用前、戴用当晚、戴用1周后的睡眠微觉醒指数均无明显差异（P>0.05）。两种咬合板戴用后,磨牙指数均降低。NTI-tss戴用前、戴用当晚和1周后的磨牙指数分别为（7.50±1.11）、（3.45±1.22）、（3.51±1.03）次·h-1,戴用当晚与戴用前、戴用1周与戴用前的差异均有统计学意义（t=26.52,t=26.12,P<0.01）。OS戴用前、戴用当晚和1周后的磨牙指数分别为（7.44±1.23）、（2.97±0.91）、（6.43±1.02）次·h-1,戴用当晚与戴用前、戴用1周与戴用前的差异也有统计学意义（t=16.79,t=3.79,P<0.01）,但与NTI-tss相比,降低程度较小。结论NTI-tss和OS对于睡眠微觉醒的发生无影响,两者都可以降低磨牙指数,但前者对于夜磨牙症的短期疗效可能更稳定。

Investigation of nociceptive trigeminal inhibitory tension suppression system and occlusal stabilization splint on bruxism patients by using polysomnography

Objective To study the short-term effects of nociceptive trigeminal inhibitory tension suppression sys-tem(NTI-tss) and occlusal stabilization splint(OS) on sleep bruxism patients.Methods Ten patients received the two splint treatments in a randomized cross-over fashion: An NTI-tss and an OS for a 1-week period,respectively.Record the bruxism episodes per hour,micro-arousals per hour of the patients before wearing the splints(baseline),the first night and 1 week after wearing the splints with polysomnography.Statistical analysis was performed with SAS 9.1 by means of mixed effect model analysis.Results There were no differences among the micro-arousal index of the base-line,the first night and 1 week later with both types of the splints(P>0.05).The NTI-tss was associated with a significant reduction in bruxism index compared with baseline.The bruxism index of baseline,the first night and 1 week later were 7.50±1.11,3.45±1.22,and 3.51±1.03 per hour(the first night vs baseline,t=26.52,P<0.01;1 week vs baseline, t=26.12,P<0.01).There were also significant differences in the bruxism index after wearing the OS.The bruxism in-dex of baseline,the first night and 1 week later were 7.44±1.23,2.97±0.91 and 6.43±1.02 per hour(the first night vs base-line,t=16.79,P<0.01;1 week vs baseline,t=3.79,P<0.01).Compared with the NTI-tss group,the reduction was much less,especially 1 week later.Conclusion Both the NTI-tss and the OS splints can reduce the bruxism index,and have no affect the incidence of micro-arousal.In this short term study,the NTI-tss was more effective than the OS for the treatment of sleep bruxism.