| 心肌挫伤后心脏肌钙蛋白-T和心肌酶谱含量的变化及其诊断作用 |
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| 引用本文： | 闵家新,朱佩芳,王正国,刘宝松,翁格文.心肌挫伤后心脏肌钙蛋白-T和心肌酶谱含量的变化及其诊断作用[J].中华实验外科杂志,2000,17(3):249-250. |
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| 作者姓名： | 闵家新 朱佩芳 王正国 刘宝松 翁格文 |
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| 作者单位： | 400042重庆,第三军医大学大坪医院野战外科研究所四室 |
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| 摘 要： | 目的 观察心脏肌钙蛋白－Ｔ（ｃａｒｄｉａｃ ｔｒｏｐｏｎｉ－Ｔ，ｃＴｎ－Ｔ）和心肌酶谱（ｍｙｏｃａｒｄｉａｌ ｅｎｚｙｍｅｓ，ＭＥ）在心肌挫伤（ｍｙｏｃａｒｄｉａｌ ｃｏｎｔｕｓｉｏｎ，ＭＣ）后含量变化及其对ＭＣ的诊断价值。方法 采用兔钝性胸部创伤（ｂｌｕｎｔ ｃｈｅｓｔ ｔｒａｎｍａ，ＢＣＴ）模型，致成中度至重度ＭＣ，分别在伤前、伤后４、８ｈ、２４ｈ测定血清ｃＴｎ－Ｔ和ＭＥ含量。结果 伤后４ｈ，
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| 关 键 词： | 心肌挫伤 心脏肌钙蛋白－T 心肌酶谱 |
The changes of cardiac troponin-T and myocardial enzymes in plasma following myocardial contusion and their diagnostic values |
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| MIN Jiaxin,ZHU Peifang,WANG Zhengguo,et al..The changes of cardiac troponin-T and myocardial enzymes in plasma following myocardial contusion and their diagnostic values[J].Chinese Journal of Experimental Surgery,2000,17(3):249-250. |
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| Authors: | MIN Jiaxin ZHU Peifang WANG Zhengguo |
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| Institution: | MIN Jiaxin,ZHU Peifang,WANG Zhengguo,et al.Research Institute of Surgery,Daping Hospital,Third Military Medical University,Chongqing 400042,China |
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| Abstract: | Objective To observe the changes of the contents of cardiac troponin T(cTn T) and myocardial enzymes (ME) in plasma following myocardial contusion (MC) and to assess their diagnostic value in MC after blunt chest trauma (BCT). Methods Utilizing the rabbit model of BCT to develop moderate to severe MC,the cTn T and ME contents pre trauma and 4, 8 h and 24 h after MC were determined.Results The contents of cTn T and ME were remarkably increased 4 to 24 h after MC ( P<0.01 ) .The contents of cTn T reached its peak and ME were slightly decreased at 24 h after MC,but they were also higher than that in pre trauma(P<0.01).Conclusion It is helpful for early diagnosis of MC after BCT to measure the changes of cTn T and ME contents in plasma.cTn T is more sensitive for diagnosis than ME in MC after BCT. |
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| Keywords: | Myocardial contusion Cardiac troponin Myocardial enzymes Blunt chest trau-ma Diagnosis |
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