Non-HIV-Related Progressive Multifocal Leukoencephalopathy (PML): A Tertiary Cancer Center Experience |
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Authors: | Sajeel Chowdhary MD Lisa M. Chalmers PA-C Marc Chamberlain MD |
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Affiliation: | Department of Interdisciplinary Oncology, MCC - NEURPROG, Tampa, FL 33612-9497, USA. |
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Abstract: | In the course of 1 year at a tertiary cancer center, 3 patients (2 men; 1 woman; age 51-75 years) were seen in neurological consultation (1.5% of all consultations). Clinical course in all patients was of a progressive neurologic disorder not consistent with either a primary or secondary malignancy. Magnetic resonance (MR) imaging was most informative with respect to diagnosis and subsequent management. Brain biopsy was performed in all patients to assist in both diagnosis and prognostication. All patients were determined to have progressive multifocal leukoencephalopathy (PML) by brain biopsy. |
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Keywords: | Progressive multifocal leukoencephalopathy non-AIDS related |
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