阳虚患者单个核及多形核白细胞糖皮质激素受体改变

本文在过去测定阳虚患者混合白细胞中糖皮质激素受体(GCR)的基础上,进一步测定这类患者的单个核白细胞(MNL)及多形核白细胞(PML)的 GCR。结果发现6例阳虚患者 MNL 的 GCR 和 PML 的 GCR 各为3473±413(±S,下同)及4433±651位点细胞,与对照组(相应为4462±962及5622±782位点/细胞)相比有显著差异(P<0.05)。同一患者分别测定 MNL、PML 及混合白细胞的 GCR 也都是相应降低,具体数字各为3369±370、4986±419及4524±852位点/细胞(5例),其中 MNL 的 GCR 较低,PML 的较高,而混合白细胞的 GCR 居中。因此,作者认为,混合白细胞的 GCR 是可以反映阳虚患者 GCR 的变化的。

Giucocorticoid Receptors on Human Peripheral Mononuclear and Polymorphonuclear Leucocytes:Changes in Patients with Yang -Deficiency

It was found that,in former works,the glucocorticoid receptors(GCR)on peripheral mixed leucocytes in patients with Yang-deficiency were decreased.In this work,the mixed leucocytes were further separated into mononuclear(MNL)and polymorphonuclear(PML)leucocytes,and GCR were determined in each part of leucocytes.GCR on MNL and PML in 6 Yang deficient patients were 3473±413 and 4433±651 sites/cell respectively,statistically significant from the normal control group(4462±962 and 5622±782 sites/cell respectively,P<0.05).GCR on MNL,PML and mixed leucocytes in 5 patients were determined simultaneously,and all lowered from the control group.The results were 3369±370,4986±419 and 4524±852 sites/cell respectively,with the lowest GCR on MNL and highest on PML.