Harman induces CYP1A1 enzyme through an aryl hydrocarbon receptor mechanism |
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| Authors: | Mohamed A.M. El Gendy |
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| Affiliation: | Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton AB, Canada T6G 2N8 |
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| Abstract: | |
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| Keywords: | AhR, aryl hydrocarbon receptor Act-D, actinomycin D CHX, cycloheximide CYP, cytochrome P450 EMSA, electrophoretic mobility shift assay EROD, 7-ethoxyresorufin O-deethylase GAPDH, glyceraldehyde-3-phosphate dehydrogenase MTT, (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) PAHs, Polycyclic aromatic hydrocarbons TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin XRE, xenobiotic responsive element |
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