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Placental p,p'-dichlorodiphenyldichloroethylene and cord blood immune markers
Authors:Kevin Brooks  Hanem Hasan  Sridhar Samineni  Venu Gangur  Wilfried Karmaus
Institution:Department of Epidemiology and Biostatistics, Norman J. Arnold School of Public Health, University of South Carolina, Columbia, SC 29208-0001, USA.
Abstract:Placental p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) concentration and cord blood atopic markers were determined in 19 neonates. Increased placental p,p'-DDE was associated with a statistically significant increase in cord plasma interleukin (IL)-13. Furthermore, both cord plasma IL-4/interferon (IFN)-gamma and IL-13/IFN-gamma ratios were significantly positively associated with placental p,p'-DDE concentration.
Keywords:dichlorodiphenyldichloroethylene  placenta  cytokines  cord  allergy
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