脑卒中后癫痫50例临床研究

目的探讨脑卒中后癫痫的临床特点，癫痫对脑卒中恢复期神经功能康复的影响。方法50例脑卒中后继发癫痫患者进行发作部位、类型、治疗时间及效果等分析，并按病情轻、中、重三组进行功能康复评分。结果脑卒中后癫痫发生率5．1%（50／980），其中早发癫痫72％（36／50），迟发癫痫28％（14／50）。皮层病灶继发癫痫72％（36／50），皮层下病灶继发癫痫占28％（14／50）。早发癫痫中全身发作27例．部分性发作9例，迟发癫痫中全身发作4例，部分性发作10例。癫痫组神经功能缺损评分均差于对照绀组（P〈0．05），结论脑卒中后癫痫皮层病灶多见，早发癫痫以全身发作为主，迟发癫痫以部分发作为主。脑卒中合并癫痫患者的治疗效果差于对照组，抗癫痫治疗有利于神经功能康复。

Clinical analysis on 50 epilepsy patients after cerebral stroke seizure

Objective To analyze the clinical features of epilepsy following cerebral stroke seizure and its effect on the recovery of neural function. Methods Fifty patients with epilepsy following cerebral stroke seizure were analyzed in their seizure location and type, treatment time and effect. All cases were scored on their neural function based on the patients' conditions (slight, moderate and severe). Results Among 980 stroke patients, 50 cases developed epilepsy (5.1%, 50/980). Among them, 34 patients developed seizures in early stage (72%, 36/50), others in late stage(28%,14/50). Among 50 cases with epilepsy, 36 cases suffered seizures located in brain cortex (72%, 36/50); others were located in sub-cortex (28%, 14/50). In early seizure, generalized tonic-clonic seizure (GTS) occurred in 25 cases and partial seizure in 9. In late seizure, 6 cases presented with generalized seizure and 10 cases with partial seizure. The scores of neural function defects (NFD) in the epilepsy group were all lower than those in the control group (P<0.05). Conclusion The epilepsy following cerebral stroke seizure usually occurred in the patients with lesions located in cerebral cortex. The epilepsy in early stage following stroke mostly presented with GTS and the one in late stage usually with partial seizure.The theraputic efficiency of the epilepsy following cerebral stroke was worse than the effect of control. The anti-epilepsy treatment is benefit for the recovery of neural function.