泛耐药鲍曼不动杆菌的临床分布及耐药性监测

目的了解泛耐药鲍曼不动杆菌感染的分布特点及耐药性。方法采用回顾性调查方法,对北京某三级甲等医院2009年3月至11月住院病人临床送检标本检出的302株泛耐药鲍曼不动杆菌分布与抗菌药物耐药状况进行了调查与分析。结果在调查期间该医院从医院感染病人标本中检出的6种耐药菌分别是耐甲氧西林金黄色葡萄球菌、泛耐药鲍曼不动杆菌、ESBL+肺炎克雷伯、ESBL+大肠爱希菌、耐万古霉素肠球菌和铜绿假单胞菌,共计867株,其中泛耐药鲍曼不动杆菌构成比为34.83%。该菌株有89.16%来自痰标本,其次是尿液,占4.20%;其主要来自ICU病人标本和呼吸病房病人标本。该菌株对临床常用抗菌药物高度耐药和多重耐药,对亚胺培南耐药率高达94.98%。结论泛耐药鲍曼不动杆菌感染主要分布于呼吸道和泌尿道感染病人,呈现出多重耐药趋势。

SURVAILLANCE ON ANTIBIOTICS RESISTANCE AND CLINICAL DISTRIBUTION OF PDR - AB

Objective To know the clinical distribution and antibiotics resistance of PDR-AB(Pan-drug resistant acinetobacter baumannii).Methods Retrospective investigation was used to analyze antibiotics resistance and clinical distribution of 302 strains of PDR-AB isolated from clinic specimens from March to November 2009 at a first hospital of three level in Beijing.Results There were 6 kinds of antibiotic-resistant bacteria of the specimens,which were MRSA,PDR-AB,KPN E+,ECO E+,VRE and PAE.The total were 867 strains.The ratio of PDR-AB was 34.83%.Of which,89.16% was detected out in the sputum samples,4.20% in urine samples.Most of PDR-AB were from ICU and the respiratory ward.PDR-AB show high-drug resistance and multi-drug resistance,resistance rate to imipenem is 94.98%.Conclusion PDR-AB mostly make respiratory tract infection and urinary tract infection,show multiple drug-resistant trend.