Biennial screening mammography is cost effective in healthy women aged over 65 years |
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| Affiliation: | 1. Department of Urology, Hospital of Vall Hebron, Autonomous University of Barcelona, Barcelona, Spain;2. Department of Urology, Fundació Puigvert, Autonomous University of Barcelona, Barcelona, Spain;3. Department of Urology, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain;4. Department of Urology, Hospital Parc Taulí, Autonomous University of Barcelona, Barcelona, Spain;5. Department of Urology, Hospital Bellvitge, University of Barcelona, Barcelona, Spain;6. Department of Urology, Hospital Germans Trias i Pujol, Autonomous University of Barcelona, Barcelona, Spain;1. Netherlands Comprehensive Cancer Organization, Utrecht, the Netherlands;2. Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden;3. Department of Urology, Radboud university medical center, Nijmegen, the Netherlands;4. Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands;5. Radboud Institute for Health Sciences, Radboud university medical center, Nijmegen, the Netherlands |
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| Abstract: | QuestionWhat is the cost-effectiveness of screening mammography in women over 65 years old?Study designSystematic review with narrative synthesis.Main resultsTen studies, out of 115 identified, met inclusion criteria. Studies had similar cost-effectiveness findings; extending biennial screening to ages 75–80 years cost, on average, $34,000–$88,000 per life year gained compared with stopping screening at age 65 (adjusted to 2002 US dollars). Two studies found breast cancer screening less effective at reducing mortality in women with significant comorbidities (dementia, congestive heart failure, or hypertension), thus reducing the cost-effectiveness of screening in this population. No study fully adjusted for potential harms of screening.Authors’ conclusionsIn women aged over 65 years without serious comorbidity, biennial breast cancer screening reduces mortality at reasonable costs. |
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