不宁腿综合征与卒中相关性的临床证据和可能机制

近年来临床报道的不宁腿综合征（restless legs syndrome，RLS）与卒中相关联的临床病例层出不穷，RLS患者罹患卒中的比例增加，卒中后出现RLS亦较常见。近年来频繁报道的RLS与卒中相关性临床研究，也认证了上述的结论。推测RLS发病机制与卒中的多项危险因素相关或重叠存在，重度的RLS增加了卒中，尤其缺血性卒中的风险，并可能成为缺血性卒中的危险因素，但RLS与卒中之间的因果关系尚需要进一步探讨。

The Clinical Evidence of Correlation between Restless Legs Syndrome and Stroke and Possible Pathogenesis

In recent years the clinical reports of clinical cases regarding restless legs syndrome (RLS) is associated with stroke emerge endlessly. RLS patients suffering from stroke are increasing, and occurrence of post-stroke RLS become more common. Recently frequent reports of the clinical studies on RLS and stroke correlation have also proved the above mentioned conclusions. Therefore, it's speculated that the pathogenesis of RLS is associated with a number of risk factors for stroke or overlap existing; severe RLS can increase the prevalence of stroke, especially the risk of ischemic stroke, which may be a risk factor for ischemic stroke. However, the causality between RLS and stroke still requires further discussion.