早期乳腺癌保乳术中低能X线放疗安全及可行性初步研究

目的 探讨早期乳腺癌保乳手术中放疗的短期并发症及美容效果。方法 回顾分析2013—2015年间30例早期乳腺癌患者资料。全部患者均行乳腺癌保乳手术及低能X线术中放疗,术中予以适配器表面20 Gy处方剂量,术后观察手术区域并发症、放射性损伤、乳房美容效果。结果无严重3、4级不良反应;短期并发症为4例(13%)出现血清肿,其中2例需要外科抽吸处理;3例(10%)出现1—2级乳腺皮肤红斑;美容效果优秀率为50%。患者均未出现LR及远处转移。结论 低能X线术中放疗在乳腺癌保乳手术中安全可行,在部分早期低危乳腺癌患者中可作为瘤床补量的一种选择参考。

Safety and feasibility of low-energy X-ray radiotherapy in breast conserving surgery for early-stage breast cancer

Objective To investigate the short-term complications and cosmetic outcomes of radiotherapy in breast conserving surgery for early-stage breast cancer. Methods A retrospective analysis was performed on clinical data from 30 patients with early-stage breast cancer from 2013 to 2015. All patients underwent breast conserving surgery combined with intraoperative low-energy X-ray radiotherapy. The prescribed dose was 20 Gy at the surface of the applicator. Local complications, radiation injury, and cosmetic outcomes were observed after surgery. Results No grade 3-4 adverse reactions were found in patients. In terms of short-term complications, four patients (13%) had seroma, two of whom needed suction treatment;three patients (10%) had grade 1-2 skin erythema. Half of the patients had excellent cosmetic outcomes. None of the patients had local recurrence or distant metastasis. Conclusions Intraoperative low-energy X-ray radiotherapy is safe and feasible in breast conserving surgery for breast cancer. It can be considered as an optional approach for tumor bed boost in some patients with early-stage low-risk breast cancer.