422例终止妊娠的梅毒患者既往随访结果分析

目的:对深圳市宝安区终止妊娠的梅毒患者的随访结果进行分析,为有针对性地开展梅毒预防与控制工作提供依据。方法:收集宝安区终止妊娠的422例梅毒患者的相关资料,并进行回顾性分析。结果:422例终止妊娠的梅毒患者中20~35岁女性357例(84.60%);经婚前性传播者194例(45.97%),婚内性传播81例(19.19%),婚外性传播32例(7.58%);潜伏梅毒321例(76.07%);422例终止妊娠的梅毒患者中人工流产者187例(44.31%),其中初筛TRUST滴度≤1∶4者129例(30.57%);自然流产者35例(8.29%),其中初筛TRUST滴度≤1∶4者22例(5.21%);死胎死产者63例(14.93%),其中初筛TRUST滴度≥1∶8者53例(12.56%);异位妊娠者137例(32.46%),其中初筛TRUST滴度≤1∶4者106例(25.12%)。378例患者(89.57%)在孕28周之前进行梅毒筛查,其中352例患者(83.41%)选择苄星青霉素治疗。69.43%的患者6个月后就失访,极少数(1.9%)终止妊娠的梅毒患者随访到两年。结论:加强梅毒孕产妇的管理对降低梅毒患者终止妊娠发生率有重要意义。

Follow-up Analysis on the Pregnancy Termination in 422 Patients with Syphilis

Objective:To analyze the follow up results of pregnancy termination in syphilis pa-tients in Bao′an District , and to provide evidences for the prevention and control measures toward syphilis.Methods:422 cases of pregnancy termination in syphilis patients were collected in Bao′an district , and were analyzed retrospectively .Results:84.60%syphilis patients with termination of pregnancy were between the age of 20 to 35 years old;45.97%syphilis patients were premarital sexual transmission , marital sexual transmission accounted for 19.19%, extramarital sexual trans-mission accounted for 7.58%;76.07%patients had latent syphilis .Artificial abortion accounted for 44.31%, 30.57%patients of them had TRUST titer ≤1∶4;8.29%patients had spontaneous abortion , and 5.21%of them also had TRUST titer ≤1∶4;stillbirth were 14.93%, and 12.56%of them had TRUST titer ≥1∶8;ectopic pregnancy accounted for 32.46%, and 25.12%of them had TRUST titer ≤1∶4 .The majority of patients ( 89.57%) have received syphilis screening be-fore 28 weeks, and most of the patients ( 83.41%) received benzathine penicillin treatment;69.43%of the patients were lost to follow-up after 6 months, very few (1.9%) syphilis patients with pregnancy termination were followed-up for two years .Conclusion:It is necessary to improve the management of pregnant women with syphilis , which has great significance in reducing the rate of pregnancy termination in syphilis patients .