| 芳基萘内酯型木脂素类化合物研究进展 |
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| 引用本文： | 孙彦君,王俊敏,陈虹,华会明.芳基萘内酯型木脂素类化合物研究进展[J].中国中药杂志,2013,38(13):2051-2059. |
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| 作者姓名： | 孙彦君 王俊敏 陈虹 华会明 |
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| 作者单位： | 河南中医学院药学院, 河南 郑州 450046;沈阳药科大学基于靶点的药物设计与研究教育部重点实验室, 辽宁 沈阳 110016;河南中医学院药学院, 河南 郑州 450046;武警医学院生药教研室, 天津 300162;沈阳药科大学基于靶点的药物设计与研究教育部重点实验室, 辽宁 沈阳 110016 |
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| 基金项目： | 河南中医学院博士科研启动基金项目(BSJJ2011-13) |
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| 摘 要： | 天然来源的芳基萘内酯型木脂素主要存在于小檗科、爵床科、橄榄科、马鞭草科、大戟科等植物中,具有较强的抗肿瘤和抗病毒活性,一直是药学工作者研究的热点领域。该文从提取分离、生物合成、结构特点、植物来源、波谱特征等方面对芳基萘内酯型木脂素进行了综述,以期为芳基萘内酯型木脂素的深入研究及合理开发利用提供参考依据。
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| 关 键 词： | 芳基萘内酯型 木脂素 研究进展 |
| 收稿时间： | 1/2/2013 12:00:00 AM |
Advances in studies on aryltetralin lactone lignans |
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| SUN Yan-jun,WANG Jun-min,CHEN Hong and HUA Hui-ming.Advances in studies on aryltetralin lactone lignans[J].China Journal of Chinese Materia Medica,2013,38(13):2051-2059. |
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| Authors: | SUN Yan-jun WANG Jun-min CHEN Hong and HUA Hui-ming |
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| Institution: | School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou 450046, China;Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China;School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou 450046, China;Pharmacognosy Division, Medical College of Chinese People's Armed Police Force, Tianjin 300162, China;Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China |
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| Abstract: | Natural aryltetralin lactone lignans existed in the plants of family Berberidaceae, Acanthaceae, Burseraceae, Verbenaceae, Euphorbiaceae, etc. Due to the antineoplastic and antiviral properties, it has become a hot research topic in medicinal chemistry. This review covers extraction and isolation, biosynthesis, plant origin, and structure and spectral characteristics of natural aryltetralin lactone lignans. It will provide a useful reference for the intensive studies and rational utilization of aryltetralin lactone lignans. |
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| Keywords: | aryltetralin lactone lignans advances in studies |
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