石榴皮、石榴瓤及石榴籽的化学成分比较研究

为比较石榴皮、石榴内瓤和石榴籽化学成分的差异,研究建立了石榴皮饮片的HPLC指纹图谱,对三者的化学成分进行了比较,并对没食子酸和鞣花酸含量进行测定。结果表明,HPLC图谱可见石榴皮与石榴瓤之间化学成分无明显差别,仅成分含量有所不同,而石榴籽与其他二者化学成分存在较大的差异。石榴皮中没食子酸和鞣花酸的质量分数分别为 0.33%,0.59%,石榴瓤中没食子酸和鞣花酸的质量分数分别为0.52%,0.38%。石榴籽中仅检测到鞣花酸,质量分数为 0.01%。由此可见,在石榴皮饮片净制过程中应去净石榴籽,以免影响饮片质量和临床疗效。内瓤在保证充分干燥的前提下,可以保留。

Comparative study of chemical composition of pomegranate peel pomegranates inside and pomegranate seeds

An HPLC fingerprint of pomegranate peel was established. Using chromatographic conditions, we compared the chemical composition of pomegranate peel, inside and seeds,and simultaneously determined the contents of gallic acid and ellagic acid. By comparison, we found that there were no significant differences between pomegranate peel and inside, but there was a big difference between pomegranate seeds and another two. The contents of gallic acid and ellagic acid of pomegranate peel respectively were 0.33%,0.59%, while in pomegranate inside the result respectively were 0.52%,0.38%. Content of ellagic acid from pomegranate seeds was only 0.01%. By study, we thought that when pomegranate peel was processed, pomegranate seeds should be removed,while pomegranate inside could be retained on the premise of full drying.