PET-CT和MRI诊断宫颈癌盆腔淋巴结转移的对比研究

目的本研究旨在对比研究PET-CT和MRI在宫颈癌盆腔淋巴结转移中的诊断价值。方法回顾性分析2008年1月-2012年9月在中国医科大学附属盛京医院接受广泛性子宫切除和盆腔淋巴结清扫术的79例宫颈癌病人资料,所有患者术前均行PET-CT和MRI检查。结果 79例病人中有22例(27.8%)存在盆腔淋巴结转移。PET/CT和MRI检测淋巴结转移的敏感度分别为31.8%和59.1%(P=0.07);PET/CT和MRI的特异度分别为86.0%和66.7%(P=0.027)。PET/CT和MRI的受试者工作特征曲线下面积分别为0.589和0.629(P=0.570)。结论 PET-CT诊断宫颈癌盆腔淋巴结转移的敏感性低于MRI,但特异性优于MRI。

Comparison between PET-CT and MRI in diagnosing pelvic lymph nodal metastasis of uterine cervical carcinoma

【Objective】To compare magnetic resonance image（MRI） with positron emission tomography/computed tomography（PET/CT） in the preoperative detection of lymph node metastases in patients with uterine cervical cancer.【Methods】This retrospective study reviewed patients with cervical cancer who had undergone both preoperative MRI and PET/CT before radical surgery,including lymphadenectomy between Jan 2008 and Sept 2012.【Resluts】Seventy-nine patients were identified,of whom 22（27.8%） had pelvic lymph node metastasis.For detecting metastatic lymph nodes,sensitivity of PET-CT and MRI was 31.8% and 59.1%,respectively（P=0.07）.The specificity of PET-CT and MRI was 86.0% and 66.7%,respectively（P=0.027）.The area under the receiver operating characteristics for the MRI and PET-CT were 0.667 and 0.561,respectively（P=0.570）.【Conclusion】PET/CT showed less sensitive and more specific than MRI for detecting metastatic lymph nodes in patients with cervical cancer.