孕妇产前血清IgG抗-A(B)效价与新生儿溶血病的相关性分析

[目的] 分析O型血孕妇产前IgG抗A(B)效价与ABO新生儿溶血病的相关性。[方法] 选择我院2012年6月-2013年7月收治的350例夫妇血型不合的O型血孕妇,分析孕妇的IgG抗A(B)效价与新生儿ABO溶血病的相关性。[结果] 不同夫妻血型配对的IgG抗A(B)效价分布差异无统计学意义(P>0.05),IgG抗A(B)效价越高新生儿溶血病发生率越高,ABO新生儿溶血病与抗A(B)效价呈现一定正比例关系(P<0.05)。[结论] 孕妇产前血清IgG抗A(B)抗体与ABO新生儿溶血病关系密切。

Correlation between prenatal serum IgG anti-A(B) titers and neonatal hemolytic disease

[Objective] To analyze the relationship between the serum IgG anti-A（B）of of preg- nant women and the hemolytic disease of newbom. [ Methods] From June 2012 to July 2013 were se- lected 350 pregnant women （ type O blood } with husband-wife ABO incompatibility treated in our hospital and the relationship was analyzed between the serum IgG anti-A （ B } of pregnant women and hemolytic dis- ease of newborn. [ Results] There were no statistical differences in IgG anti-A （ B } titers distribution （ P 〉 0.05 ） resulting from different blood type matching of husband and wife. The incidence of the rate of hemolytic disease of newborn was increased with the higher serum IgG blood group antibody titer of pregnant women （P 〈 0.05 ）. [ Conclusion] There is a close relationship between the serum IgG anti-A（B） of pregnant women and hemolytic disease of newbom.