原发性肝癌患者血清 D - 二聚体和同型半胱氨酸检测的临床价值简

目的为探讨原发性肝癌（PHC）患者血清D二聚体和同型半胱氨酸（Hcy）联合检测的临床价值。方法采用日本OLYMPUS公司AU2700全自动生化分析仪及法国StagoSTA—REvolution全自动血凝仪对100例PHC患者，80例良性肝病患者及60例健康体检者血清D二聚体和Hcy分别进行检测，并进行比较。结果原发性肝癌（PHC）患者血清D二聚体和Hey水平高于良性肝病患者和健康体检者，差异有统计学意义（P〈0．01）；良性肝病患者血清D二聚体和Hcy水平与健康体检者比较，差异无统计学意义（P〉0．05）。结论血清D二聚体与Hcy联合检测对肝肿瘤的良恶性辅助诊断及鉴别诊断具有一定的临床价值。

Clinical Valueof D-dimer and Homocysteine Detection in Patients with Primary Hepatocellular Carcinoma

Objective To investigate the hepatocellular carcinoma （PHC） in 100 patients with serum D- dimer and homocysteine （Hcy） and clinical value of combined detection. Methods the Japanese compa- ny OLYMPUS AU2700 automatic biochemical analyzer and the French Stago STA-R Evolution automatic blood coagulation analyzer in 100 patients with PHC ,80 patients with benign liver disease patients and 60 cases of healthy serum D- dimer and Hcy were detected, and compared. Results Primary hepatocellular carcinoma （PHC） in patients with serum D- dimer and Hey level is higher than that of benign disease patients and healthy controls, the difference was statistically significant （P 〈0.01 ） ; benign liver disease patients serum D- dimer and Hcy leveland healthy subjects ,no significant difference （P 〉 0.05 ）. Conclusion serum D- di- mer and Hcy combined detection of liver tumor assisted diagnosis and differentialdiagnosis has certain clinical value.