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不同剂量糖皮质激素对重症支气管哮喘的疗效观察
引用本文:李金明,李秀芳.不同剂量糖皮质激素对重症支气管哮喘的疗效观察[J].山东医学高等专科学校学报,2000,22(2):89-90.
作者姓名:李金明  李秀芳
作者单位:[1]临沂医专附属临沂市人民医院 [2]临沂妇幼保健院
摘    要:目的 观察不同剂量的糖皮质扩素对重症支气管哮喘的疗效。方法 观察组16例采用小剂量激素(地塞米松20mg/d)治疗,对照组16例使用较大量激素(地塞米松40mg/d)治疗。基他治疗措施及方法基本桢。结果 两组病人症状均在1~2d缓解,动脉血PaO2恢复正常所需时间两组无差异(P〉0.05)。结论 对重症哮喘者早期应用小剂量激素、氩茶碱持续静脉点滴,可避免大剂量应用产生的副作用,可收到较好效果。

关 键 词:支气管哮喘  糖皮质激素  药物疗法  疗效

APPLICATION OF DIFFERENT DOSES OF GLUCOCORTICOIDS TO THE TREATMENT OF PATIENTS WITH SEVERE BRONCHIAL ASTHMA
Li Jinming,Li Xiufang,Li Xinhua,et al.APPLICATION OF DIFFERENT DOSES OF GLUCOCORTICOIDS TO THE TREATMENT OF PATIENTS WITH SEVERE BRONCHIAL ASTHMA[J].Journal of Shandong Medical College,2000,22(2):89-90.
Authors:Li Jinming  Li Xiufang  Li Xinhua  
Abstract:Objective To compare the therapeutic effects of applying different doses of glucocorticoids to patients with severe bronchial asthma.Methods 16 cases in the treatment group were treated with low dose glucocorticoids(dexamethasone,20 mg/d),and other 16 cases in the control group with high dose glucocorticoids(dexamethasone,40mg/d).Other management was alike.Results The clinical symptoms were improved in both groups in 12 days.The difference of the demanding time that the arterial blood gas(PaO 2)returned to normal between the two groups was insignificant (P>0.05) .Conclusion To start intravenous drips of low dose glucocorticoids and aminophylline as soon as possible is effective in treating patients with severe bronchial asthma and this can avoid some side effects caused by the application of high dose glucocorticoids.
Keywords:Severe bronchial asthma  Glucocorticoids
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