Primary cutaneous CD30-positive large cell lymphoma |
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Authors: | Isabel Cristina Freitas† Raquel Vieira† Ana Afonso§ Assis Pacheco† Prates Nunes† |
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Institution: | Department of Dermatology, Curry Cabral Hospital, Lisbon, Portugal. isabel.cristina.freitas@ip.pt |
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Abstract: | Primary cutaneous CD30-positive large cell lymphoma is a recently described entity, recognized by immunohistochemical criteria. Spontaneous regression may occur and although relapses are frequent, most patients have a favourable prognosis. We describe a 83-year-old woman with a large ulcerated tumour on her right forearm, with 2 months evolution. Histological and immunohistochemical examination revealed a CD30-positive large cell lymphoma. Systemic involvement was not detected. The tumour regressed spontaneously. Cutaneous relapses occurred one year later, all with spontaneous regression. After a 2-year follow-up period, the patient is well, without concurrent extracutaneous disease. This case is in keeping with other reports of spontaneous regression and favourable outcome of this type of cutaneous lymphoma. |
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Keywords: | anaplastic large cell lymphoma cutaneous T-cell lymphoma CD30 antigen Ki-1 antibody |
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