纤维跟踪技术在模拟显示人脑联络纤维中的应用

目的：应用弥散张量（DTI）纤维跟踪技术来模拟显示脑的联络纤维，探讨结果与经典解剖学知识的一致性。方法：对1个志愿者行单次激发回波平面弥散张量成像，利用纤维跟踪技术来模拟显示其联络纤维，并观察与经典解剖学知识的一致性。结果：通过选择恰当的感兴趣区，各向异性阈值、角度阈值、步长和体素内采样数目等参数，利用弥散张量纤维跟踪技术可模拟显示扣带、上枕额束、下枕额束、钩束、下纵束等联络纤维。结论：利用弥散张量纤维跟踪技术可模拟显示人脑联络纤维，且与经典解剖学有高度一致性，是在活体中研究人脑联络纤维的一种新方法。

Analog presentation of association fibers of human brain by the diffusion tensor magnetic resonance tractography

Objective: To visualize association fibers of human brain by the method of diffusion tensor magnetic resonance tractography, and to investigate its consistency with the classic anatomy. Methods: single shot echo-planar diffusion tensor imaging was performed in 1 volunteer, and then the associate fibers were visualized in MR workstation. Finally the consistency between reconstructed associate fibers and that from the classic anatomy were compared. Results: By selecting proper regions of interest (ROI) and FA threshold , angle threshold , step size and number of sampling in a voxel length, diffusion tensor tractography could visualize associate fibers of human brain, such as superior longitudinal fasciculus, inferior longitudinal fasciculus, superior fronto-occipital fasciculus, inferior fronto-occipital fasciculus, uncinate fasciculus, cingulum, which were well consistent with the structures of association fibers from classic anatomy. Conclusions: Association fibers of human brain can be visualized by diffusion tensor tractography and the result are highly consistent with classic anatomical features. Tractography is a new method to study association fiber of human brain.