|
|||||
|
|
| Ku70在卵巢浆液性肿瘤组织中的表达及意义 | |
| 引用本文： | 由卫芝,张师前,申爱方,李玉红,张玲,袁爱静.Ku70在卵巢浆液性肿瘤组织中的表达及意义[J].山东大学学报(医学版),2011,49(12):128-131. |
| 作者姓名： | 由卫芝 张师前 申爱方 李玉红 张玲 袁爱静 |
| 作者单位： | 1. 山东大学齐鲁医院妇产科,济南250012;聊城市人民医院妇产科,山东聊城252000 2. 山东大学齐鲁医院妇产科,济南,250012 3. 聊城市人民医院妇产科,山东聊城,252000 |
| 摘 要： | 目的 探讨Ku70在卵巢浆液性肿瘤组织中的表达及临床意义.方法 免疫组化方法检测20例正常卵巢、100例卵巢浆液性肿瘤(卵巢浆液性爱腺瘤30例、卵巢交界性浆液性囊腺瘤20例和卵巢浆液性囊腺癌50例)组织中Ku70的表达,分析其表达与临床病理参数之间的相关性.结果 Ku70在正常卵巢组织,良性、交界性和恶性卵巢浆液性组织中都有不同程度的表达,且在交界性和恶性卵巢浆液性组织中的表达明显高于正常卵巢组织和卵巢囊腺瘤(P＜0.01),卵巢癌组织分化程度越差Ku70的阳性率越高,表达强度亦越强,与肿瘤的临床分期、腹水、淋巴结转移均相关(P＜0.05).结论 Ku70的异常表达与卵巢浆液性肿瘤恶变相关. |
| 关 键 词： | 卵巢肿瘤 免疫组化 Ku70蛋白 |
Expression and significance of Ku70 in serous ovarian tumors |
|
| YOU Wei-zhi , ZHANG Shi-qian , SHEN Ai-fang , LI Yu-hong , ZHANG Ling , YUAN Ai-jing.Expression and significance of Ku70 in serous ovarian tumors[J].Journal of Shandong University:Health Sciences,2011,49(12):128-131. | |
| Authors: | YOU Wei-zhi ZHANG Shi-qian SHEN Ai-fang LI Yu-hong ZHANG Ling YUAN Ai-jing |
| Institution: | YOU Wei-zhi1,2,ZHANG Shi-qian1,SHEN Ai-fang2,LI Yu-hong2,ZHANG Ling2,YUAN Ai-jing2 |
| Abstract: | Objective To explore expression and clinical significance of the Ku70 protein in serous ovarian tumors.Methods Expression of Ku70 was detected by SP immunohistochemistry in 20 specimens of normal ovarian tissues and 100 specimens of serous ovarian tumors(30 specimens of serous cystadenoma,20 specimens of borderline serous cystadenoma,and 50 specimens of serous cystadeno-carcinoma).The correlation of Ku70 expression and clinico-pathological characteristics of serous ovarian tumors was analyzed by the Chi-squ... |
| Keywords: | Ovarian tumors Immunohistochemistry Ku70 protein |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |