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| 维生素E对孕鼠及胎鼠脑组织受手机辐射影响的保护作用 | |
| 引用本文： | 张静,张裕华,姜荣平,廉志顺,王慧,罗芮,郭冬梅,崔唏. 维生素E对孕鼠及胎鼠脑组织受手机辐射影响的保护作用[J]. 山东大学学报(医学版), 2011, 49(9): 33-36 |
| 作者姓名： | 张静 张裕华 姜荣平 廉志顺 王慧 罗芮 郭冬梅 崔唏 |
| 作者单位： | 1. 山东大学公共卫生学院卫生检验研究所,济南,250012 2. 山东大学附属千佛山医院放射科,济南,250014 3. 山东省化工研究院,济南,250014 |
| 基金项目： | 山东省自然科学基金资助课题(Y2007C086) |
| 摘 要： | 目的研究妊娠期补充维生素E对母鼠及胎鼠脑组织受手机辐射影响的保护作用。方法 40只受孕大鼠随机分为5组,自妊娠第1天起,维生素E低、中、高剂量组分别按5 mg/kg、15 mg/kg、30 mg/kg的剂量补充,阴性对照组和阳性对照组灌服脱维生素E的花生油,同时给予1 h/次、3次/d的手机辐射,连续辐射21 d,分娩后测定母鼠及胎鼠脑组织总抗氧化能力(T-AOC)和ATP酶(Na+-K+-ATP酶和Ca+-Mg+-ATP酶)的活力变化。结果阳性对照组T-AOC、Na+-K+-ATP酶、Ca+-Mg+-ATP酶活性均较阴性对照组下降(P<0.05)。与阳性对照组比较,维生素E各剂量组T-AOC含量升高,其中,母鼠维生素E中、高剂量组较阳性对照组升高,胎鼠维生素E低、中、高剂量组均高于阳性对照组(P<0.05)。母鼠维生素E各剂量组Na+-K+-ATP酶和Ca+-Mg+-ATP酶活力均高于阳性对照组,胎鼠维生素E中、高剂量组ATP酶活力较阳性对照组升高(P<0.05)。结论维生素E对受手机辐射影响的母鼠及胎鼠的抗氧化能力和能量代谢有一定的保护作用。 |
| 关 键 词： | 维生素E 手机辐射 总抗氧化能力 ATP酶 大鼠,Wistar |
Protective effects of vitamin E against electromagnetic radiation from cell phones in pregnant and fetal rats' brain tissues |
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| ZHANG Jing,ZHANG Yu-hua,JIANG Rong-ping,LIAN Zhi-shun,WANG Hui,LUO Rui,GUO Dong-mei,CUI Xi. Protective effects of vitamin E against electromagnetic radiation from cell phones in pregnant and fetal rats' brain tissues[J]. Journal of Shandong University:Health Sciences, 2011, 49(9): 33-36 | |
| Authors: | ZHANG Jing ZHANG Yu-hua JIANG Rong-ping LIAN Zhi-shun WANG Hui LUO Rui GUO Dong-mei CUI Xi |
| Affiliation: | ZHANG Jing1,ZHANG Yu-hua2,JIANG Rong-ping3,LIAN Zhi-shun1,WANG Hui1,LUO Rui1,GUO Dong-mei1,CUI Xi1 (1.Department of Chemical and Bacterial Detection,School of Public Health,Shandong University,Jinan 250012,China,2.Department of Radiology,Qianfoshan Hospital Affiliated to Shandong University,Jinan 250014,3.Shandong Province Academy of Chemical Technology,China) |
| Abstract: | Objective To investigate protective effects of maternal vitamin E supplement against electromagnetic radiation from cell phones in pregnant and fetal rats' brain tissues.Methods 40 pregnant rats were randomly divided into five groups.Low,middle and high dosages of vitamin E groups were supplemented with 5 mg/kg,15 mg/kg,and 30 mg/kg of vitamin E,respectively.The negative control group and the positive control group were given peanut oil which had vitamin E removed.All groups were exposed to a certain intens... |
| Keywords: | Vitamin E Electromagnetic radiation from cell phones Total anti-oxidant capacity ATP enzyme Rats Wistar |
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