| HPLC法测定茵芩口服液中黄芩苷的含量 |
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| 引用本文： | 宋青,金芳,孟宪波. HPLC法测定茵芩口服液中黄芩苷的含量[J]. 齐鲁药事, 2011, 30(9): 509-510 |
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| 作者姓名： | 宋青 金芳 孟宪波 |
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| 作者单位： | 淄博市药品检验所,山东,淄博,255086 |
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| 摘 要： | 目的建立以高效液相色谱法测定茵芩口服液中黄芩苷含量的方法.方法色谱柱为InertsilODS-SP(4.6mm×150mm,5μm);流动相为甲醇-0.5%磷酸(45∶55);检测波长为280 nm;流速为1.0mL·min-1.结果黄芩苷在0.061～1.830mg(r=0.999 8)线性关系良好,平均回收率为102.82%,RSD为1.2%.结论本法简便、快速、重复性好,可用于茵芩口服液的质量控制.
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| 关 键 词： | 茵芩口服液 黄芩苷 含量测定 高效液相色谱法 |
Determination of baicalin in Yinqin Oral Liquid by HPLC |
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| SONG Qing,JIN Fang,MENG Xian-bo. Determination of baicalin in Yinqin Oral Liquid by HPLC[J]. qilu pharmaceutical affairs, 2011, 30(9): 509-510 |
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| Authors: | SONG Qing JIN Fang MENG Xian-bo |
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| Affiliation: | SONG Qing,JIN Fang,MENG Xian-bo(Zibo Institute for Drug Control,Zibo 255086,China) |
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| Abstract: | Objective To establish an HPLC method for the determination of baicalin in Yinqin Oral Liquid.Methods Sample was separated on Inertsil ODS-SP（4.6 mm×150 mm,5 μm）column and the detection wavelength was 280 nm.The mobile phase was methanol-0.5% phosphoric acid（45∶ 55）.The flow rate was 1.0 mL·min-1.Results The linear range of baicalin was 0.061～1.830 mg（r=0.999 8）.The average recovery was 102.82% with the RSD was 1.2%.Conclusion The method was simple,fast,reproducible,and it can be used for the quality control of Yinqin Oral Liquid. |
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| Keywords: | Yinqin Oral Liquid Baicalin Determination HPLC |
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