乙肝病毒感染与原发性肝癌关系的血清学调查

目的　了解乙肝病毒感染与原发性肝癌的关系。　方法　对 2 11例原发性肝癌病人进行乙型肝炎病毒感染血清标志物 ( HBV- M)检测 ,并与同期 2 2 0例非肝癌消化道肿瘤病人检测的 HBV- M进行对比分析。　结果　肝癌组HBV- M阳性 186例 ( 88.15 % ) ,非肝癌组 HBV- M阳性 87例 ( 3 9.5 5 % ) ,有显著差异 ( P<0 .0 0 1)。肝癌组乙肝病毒感染以“小三阳”为主 ,“小三阳”指标为阳性者占 12 1例 ( 60 .75 % ) ,明显高于非肝癌组“小三阳”阳性 3 1例 ( 3 5 .63 % )。　结论　乙肝病毒感染在原发性肝癌病因学中起着十分重要的作用

A Serological Investigation on Relationship Between the Infection Rate of HBV and the PHC

Objective We have done the clinical tests on the HBV-M from 211 cases suffering from PHC,Meanwhile,we have also carried out comparison analysis on the HBV -M from 220 cases with tumours of digestive tracts but without hepatic cancers. Methods The results show that the HBV-M of 186 cases with hepatic cancer is positive(occupying 88.15%),while that the HBV-M of only 87 cases without hepatic cancers is positive(occupying 39.55%). Result Judging from the results of the test,we know there are markable differences between the patients with hepatic cancer and those without hepatic cancers. Among the 211 patients, 121cases' HBsAg,HBeAb,and HBcAb of the infection of Type B-hepatitis virus are positive(60.75%), which are obviously higher than those of the cases without hepatic cancer. There are only 31 cases nositive with HBsAg,HBeAb and HBcAb in non-hepatic cancer group(occupying 35.63%). Conclusion HBV infection plays an important role in pltc pathology.