Flow visualization of a pediatric ventricular assist device during stroke volume reductions related to weaning |
| |
Authors: | Roszelle Breigh N Deutsch Steven Weiss William J Manning Keefe B |
| |
Institution: | (1) Department of Bioengineering, The Pennsylvania State University, 205 Hallowell Building, University Park, PA 16802, USA;(2) Department of Surgery, Pennsylvania State Milton S. Hershey Medical Center, Hershey, PA 17003, USA; |
| |
Abstract: | The aim of this study is to define the fluid mechanics of a pulsatile pneumatically driven pediatric ventricular assist device
(PVAD), for the reduced flow rates encountered during device weaning and myocardial recovery, and relate the results to the
potential for thromboembolic events. We place an acrylic model of the PVAD in a mock circulatory loop filled with a viscoelastic
blood analog and operate at four stroke volumes (SVs), each with two different filling conditions, to mimic how the flow rate
of the device may be reduced. Particle image velocimetry is used to acquire flow field data. We find that a SV reduction method
provides better rotational flow and higher wall shear rates than a beat rate reduction method; that a quick filling condition
with a compressed diastolic time is better than a slow filling condition; and, that a reduction in SV to 40% led to greatly
reduced fluid movement and wall shear rates that could increase the thrombogenicity of the device. SV reduction is a viable
option for flow reduction during weaning, however, it does lead to significant changes to the device flow field and future
studies are needed to develop operational protocols for the PVAD during bridge-to-recovery. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|