依达拉奉治疗急性脑梗死的临床观察

目的：探讨依达拉奉对急性脑梗死治疗的临床疗效。方法：将130例急性脑梗死患者分为依达拉奉治疗组和对照组（常规治疗）,每组65例,两组均给予血小板聚集抑制剂、改善微循环药物和神经营养药物等基础治疗。将两组患者治疗前后神经功能缺损评分（NIHSS）之差和血液动力学指标进行对比分析。结果：治疗前与治疗后神经功能缺损评分之差两组差异有统计学意义（P〈0.05）,血流动力学指标中除纤维蛋白原外差异无统计学意义（P〉0.05）。结论：在脑梗死急性期依达拉奉对缺血大脑组织具有保护作用,对血流动力学无明显影响,合并出血的风险小。

Clinical observation of Edaravone in Treatment of Acute Cerebral Infarction

Objective： To study the therapeutic effect of edaraveone in treatmenrt of cerebral infarction.Methods：130 cases of acute cerebral infarction patients were divided into edaravone treatment group（n=65）and control group（n=65）（conventional treatment）,two groups were given platelet aggregation inhibitors,improve the microcirculation neurotrophic drugs and basic drugs therapy.Two groups of patients with neurological deficit score（NIHSS） of bad and hemodynamic indexes were analyzed.Results：Before and after treatment of neurological deficit score bad there is significant difference between the two groups（P0.05）,hemodynamic indexes had no statistical difference（P0.05）.Conclusion：In patients with acute cerebral infarction of edaravone on ischemic brain tissue has a protective effect on hemodynamics,no significant effect on the risk of hemorrhage small.