| 增食欲素与能量平衡 |
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| 引用本文： | 廖丽萍,刘礼斌.增食欲素与能量平衡[J].国际内分泌代谢杂志,2006,26(1):9-11. |
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| 作者姓名： | 廖丽萍 刘礼斌 |
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| 作者单位： | 350001,福州,福建医科大学附属协和医院;福建省内分泌研究所 |
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| 摘 要： | 增食欲素是一种下丘脑神经肽,在调节摄食、能量代谢平衡、睡醒周期、血压等方面有广泛作用。增食欲素神经元对血糖、血脂和瘦素、糖皮质激素有高度反应性,并通过改变摄食和代谢率来调节能量平衡。增食欲素受体1拮抗剂(SB334867)可以抑制摄食和减轻体重,成为潜在的治疗肥胖的药物。
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| 关 键 词： | 增食欲素 能量平衡 代谢 肥胖 |
| 收稿时间： | 2005-06-26 |
| 修稿时间： | 2005-06-26 |
Orexins and energy homeostasis |
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| LIAO Li-ping,LIU Li-bin.Orexins and energy homeostasis[J].International JOurnal of Endocrinology and Metabolism,2006,26(1):9-11. |
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| Authors: | LIAO Li-ping LIU Li-bin |
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| Institution: | Department of Endocrinology, Union Hospital, Fujian Medical University; Fujian Institute of Endocrinology, Fuzhou 350001, China |
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| Abstract: | Orexin is one of the hypothalamic neuropeptides, involved in the control of many physiological functions including feeding, energy metabolic homeostasis,the sleep/wake cycle,blood pressure and so on.Orexin neurons are sensitive to plasma glucose,lipids,leptin and the glucocorticoids status,and regulate energy homeostasis through altering the feeding behavior and metabolic rate. The orexin-1 receptor antagonist(SB-334867) can inhibit feeding and reduce body weight,so has potential effects as an anti-obesity agent. |
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| Keywords: | Orexins Energy homeostasis Metabolism Obesity |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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