A specific method of glycosylated hemoglobin using furosine measurement |
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Authors: | M Oimomi S Nishimoto S Matsumoto H Hatanaka K Ishikawa S Baba |
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Institution: | The Second Department of Internal Medicine, Kobe University School of Medicine, Chuo-ku, Kobe, 650, Japan |
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Abstract: | In order to get an accurately specific determination of glycosylated hemoglobin (GHb-f), the furosine assay method, which can detect epsilon-amino-lysine-bound glucose, was investigated. A good correlation was found between GHb-f values obtained by this method and HbA1 values by conventional ion exchange column chromatography. It was, therefore, considered that this technique would be a new useful method for determining glycosylated hemoglobin. |
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Keywords: | Glycosylated hemoglobin Fructose-lysine Furosine Diabetes mellitus |
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