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A specific method of glycosylated hemoglobin using furosine measurement
Authors:M Oimomi  S Nishimoto  S Matsumoto  H Hatanaka  K Ishikawa  S Baba
Institution:The Second Department of Internal Medicine, Kobe University School of Medicine, Chuo-ku, Kobe, 650, Japan
Abstract:In order to get an accurately specific determination of glycosylated hemoglobin (GHb-f), the furosine assay method, which can detect epsilon-amino-lysine-bound glucose, was investigated. A good correlation was found between GHb-f values obtained by this method and HbA1 values by conventional ion exchange column chromatography. It was, therefore, considered that this technique would be a new useful method for determining glycosylated hemoglobin.
Keywords:Glycosylated hemoglobin  Fructose-lysine  Furosine  Diabetes mellitus
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